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536-43-6 - Dyclonine hydrochloride - 1-(4-Butoxyphenyl)-3-(1-piperidinyl)-1-propanone - J61330 - Alfa Aesar

J61330 Dyclonine hydrochloride

CAS-Nummer
536-43-6
Synonyme
1-(4-Butoxyphenyl)-3-(1-piperidinyl)-1-propanone

Größe Preis ($) Menge Verfügbarkeit
5g 75,90
25g 219,00
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Dyclonine hydrochloride

MDL
MFCD00035386
EINECS
208-633-6

Chemische Eigenschaften

Formel
C18H27NO2•HCl
Molmasse
325.88
Form
Crystalline powder
Schmelzpunkt
173-178°
Löslichkeit
Partly soluble in water. Soluble in chloroform, ethanol, acetone and methanol.

Anwendungen

Dyclonine hydrochloride is used for the temporary relief of the following occasional mouth and throat symptoms: pain, minor irritation, sore mouth and sore throat. It is a sodium channel blocker and a HSP90 chaperone protein inhibitor. It shows local anesthetic effects in vivo and is orally active.

Bemerkungen

Stable under recommended storage conditions. Incompatible with oxidizing agents.

Literaturverweise

H.J.Florestano; M.E.Bahler. Antimicrobial properties of dyclonine hydrochloride, a new topical anesthetic. Journal of the American Pharmaceutical Association. 1956, 45,(5), 320-325.

 

D.D.S., R.S.Ping; D.D.S., J.G.White; D.D.S., L.B.Spear. Dyclonine hydrochloride as a topical anesthetic in dentistry: A preliminary report. Oral Surgery, Oral Medicine, Oral Pathology. 1957, 10,(6), 623-626.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H301-H315-H318-H335

Toxic if swallowed. Causes skin irritation. Causes serious eye damage. May cause respiratory irritation.

Sicherheitshinweise: P260-P201-P280g-P304+P340-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,3473
Harmonized Tariff Code
2933.39
TSCA
No
RTECS
UG8750000

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