Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

49745-95-1 - Dobutamine hydrochloride - J61333 - Alfa Aesar

J61333 Dobutamine hydrochloride

CAS-Nummer
49745-95-1
Synonyme

Größe Preis ($) Menge Verfügbarkeit
250mg 76,40
1g 248,00
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

Dobutamine hydrochloride

MDL
MFCD00153795
EINECS
256-464-1

Chemische Eigenschaften

Formel
C18H23NO3•HCl
Molmasse
337.85
Form
Off-white to white powder
Schmelzpunkt
184-186°
Löslichkeit
Soluble in water or ethanol with warming. Also soluble in methanol

Anwendungen

Dobutamine hydrochloride is a catecholamine that acts as a β-adrenergic receptor agonist with potent positive inotropic effects in vivo. It has its strongest effects on β1 receptors, with lesser but significant β2 receptor activation and only weak α1 receptor actions. As a result, it strongly increases cardiac contractility with modest chronotropic, arrhythmogenic, and vascular side effects. It is also a polyphenolic antioxidant and can inhibit all human carbonic anhydrase isoforms with Ki values near 1 ?M.

Bemerkungen

Solutions oxidize readily at pH greater than 11. Protect solutions from light

Literaturverweise

R.R.Tuttle; J.Mills. Dobutamine: development of a new catecholamine to selectively increase cardiac contractility. Circulation Research. 1975, 36,(1), 185-196.

 

Y.Huang; K.H.Kwok; N.W.Chan; C.W.Lau; Z.Y.Chen. Role of endothelium and K+ channels in dobutamine-induced relaxation in rat mesenteric artery. Clinical and Experimental Pharmacology and Physiology. 1998, 25,(6), 405-411.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H302-H312-H332-H361

Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled. Suspected of damaging fertility or the unborn child.

Sicherheitshinweise: P201-P261-P280-P304+P340-P405-P501a

Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,3395
Harmonized Tariff Code
2922.29
TSCA
No

Empfohlen

  • 36315

    Manganese powder, -325 mesh, 99.95% (metals basis)
  • 14283

    Magnesium iodide, ultra dry, 99.996% (metals basis)
  • H51762

    4'-Bromobiphenyl-3-carboxylic acid, 95%
  • L14858

    4-Cyano-4-(3,4-dichlorophenyl)cyclohexanone, 98%
  • H61137

    4'-Bromo-2'-hydroxyacetophenone, 95%

Kürzlich angesehen

Chemikalien

Life science

Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf