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Neomycin sulfate is an aminoglycoside antibiotic and calcium channel protein inhibitor. Neomycin sulfate also binds to prokaryotic ribosomes inhibiting translation and is effective against gram-positive and gram-negative bacteria. Neomycin sulfate inhibits Phospholipase C via binding to inositol phospholipids. It also inhibits phosphatidylcholine-PLD activity and induces Ca2+ mobilization and PLA2 activation in human platelets. Neomycin sulfate inhibits DNase I induced DNA degradation.
Nandi Zhou.; Jingyuan Wang.; Juan Zhang.; Can Li.; Yaping Tian.; Joseph Wang. Selection and identification of streptomycin-specific single-stranded DNA aptamers and the application in the detection of streptomycin in honey. Talanta. 2013, 108 109-116.
Xiaojing Bai.; Hui Hou.; Bailin Zhang.; Jilin Tang. Label-free detection of kanamycin using aptamer-based cantilever array sensor. Biosensors and Bioelectronics. 2014, 56, 112-116.
Gefahrenhinweise (EU): H334-H317
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