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4759-48-2 - 13-cis-Retinoic acid - Isotretinoin - J61666 - Alfa Aesar

J61666 13-cis-Retinoic acid

CAS-Nummer
4759-48-2
Synonyme
Isotretinoin

Größe Preis ($) Menge Verfügbarkeit
500mg 180,00
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13-cis-Retinoic acid

MDL
MFCD00079542
EINECS
225-296-0

Chemische Eigenschaften

Formel
C20H28O2
Molmasse
300.44
Form
Powder
Schmelzpunkt
172-175°
Löslichkeit
Soluble in chloroform, dimethyl sulfoxide, water, ethanol, and ether.

Anwendungen

13-cis-Retinoic acid is used to inhibits cell proliferation and induces cell differentiation. 13-cis-Retinoic acid is primarily used in the treatment of severe recalcitrant nodular acne.

Bemerkungen

Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Literaturverweise

Guglielmo Dusi.; Valentina Gamba. The treatment of severe cystic acne with 13-cis-retinoic acid, Evaluation of sebum production and the clinical response in a multiple-dose trial. Journal of the American Academy of Dermatology. 1999, 835,(1-2), 243-246.

Lawrence N. Farrell.; John S. Strauss.; Anna M. Stranieri. Assessment of degradation of 18 antibiotics in the Closed Bottle Test. Chemosphere. 1980, 3,(6), 602-611.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H360-H335

Causes skin irritation. Causes serious eye irritation. May damage fertility or the unborn child. May cause respiratory irritation.

Sicherheitshinweise: P201-P261-P280-P305+P351+P338-P405-P501a

Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,5228
Harmonized Tariff Code
2936.21
TSCA
Yes
RTECS
VH6440000

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