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134036-52-5 - Tyrphostin B42, 99+% - Tyrphostin AG-490 - N-Benzyl-2-(3,4-dihydroxybenzylidene)cyanoacetamide - J61715 - Alfa Aesar

J61715 Tyrphostin B42, 99+%

CAS-Nummer
134036-52-5
Synonyme
Tyrphostin AG-490
N-Benzyl-2-(3,4-dihydroxybenzylidene)cyanoacetamide

Größe Preis ($) Menge Verfügbarkeit
25mg 183,34
100mg 262,40
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Tyrphostin B42, 99+%

MDL
MFCD00236452

Chemische Eigenschaften

Formel
C17H14N2O3
Molmasse
294.31
Form
Powder
Schmelzpunkt
216-220°
Löslichkeit
Soluble in DMSO or ethanol

Anwendungen

Tyrphostin B42 is used in acute lymphoblastic leukemia studies the compound has been reported to inhibit JAK2 from B cell precursors.

Bemerkungen

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Literaturverweise

Richard C.G. Pollok.; Michael J.G. Farthing.; Mona Bajaj-Elliott.; Ian R. Sanderson.; Vincent McDonald. Interferon gamma induces enterocyte resistance against infection by the intracellular pathogen Cryptosporidium parvum. Gastroenterology. 2001, 120,(1), 99-107.

Mirjana Poljakovic.; Jens M. Nygren.; Katarina Persson. Signalling pathways regulating inducible nitric oxide synthase expression in human kidney epithelial cells. European Journal of Pharmacology. 2003, 496,(1-3), 21-28.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Harmonized Tariff Code
2926.90
TSCA
No

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