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An aminocyclitol antibiotic that binds to the 30S ribosomal subunit of bacteria and interrupts protein synthesis Spectinomycin dihydrochloride pentahydrate is used as an aminocyclitol antibiotic derived from streptomyces spectabilis. It is used in cell culture applications as well as involved in the treatment of gonorrhea. Further, it is used as an anti-bacterial agent to prevent contamination and as a selection agent for resistant bacteria and plant cells.
Korte, H. L.; Saini, A.; Trotter, V. V.; Butland, G. P.; Arkin, A. P.; Wall, J. D. Independence of nitrate and nitrite inhibition of Desulfovibrio vulgaris Hildenborough and use of nitrite as a substrate for growth. Environ. Sci. Technol. 2015, 49 (2), 924-931.
Pernil, R.; Picossi, S.; Herrero, A.; Flores, E.; Mariscal, V. Amino Acid Transporters and Release of Hydrophobic Amino Acids in the Heterocyst-Forming Cyanobacterium Anabaena sp. Strain PCC 7120. Life 2015, 5 (2), 1282-1300.