Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

88899-55-2 - Bafilomycin A1 - J61835 - Alfa Aesar

J61835 Bafilomycin A1

CAS-Nummer
88899-55-2
Synonyme

Größe Preis ($) Menge Verfügbarkeit
1mg 252,00
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

Bafilomycin A1

MDL
MFCD06795130

Chemische Eigenschaften

Formel
C35H58O9
Molmasse
622.83
Form
Oil or film
Löslichkeit
Soluble in methanol, ethanol, acetone and chloroform. Insoluble in water.

Anwendungen

Bafilomycin A1 is a specific potent inhibitor of vacuolar ATPases.It is used as an antibacterial, antifungal, antineoplastic and an immunosuppressive. It prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes and is a macrolide antibiotic and potent and selective inhibitor of vacuolar-type H+ ATPase (V-ATPase).

Bemerkungen

Store in cool place. Incompatible with strong oxidizing agents.

Literaturverweise

Miao, Y.; Li, G.; Zhang, X.; Xu, H.; Abraham, S. N. A TRP Channel Senses Lysosome Neutralization by Pathogens to Trigger Their Expulsion. Cell 2015, 161 (6), 1306-1319.

Lee, K. I.; Kim, M. J.; Koh, H.; Lee, J. I.; Namkoong, S.; Oh, W. K.; Park, J.The anti-hypertensive drug reserpine induces neuronal cell death through inhibition of autophagic flux. Biochem. Biophys. Res. Commun. 2015, 462 (4), 402-408.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Beilstein
4730700
Harmonized Tariff Code
2941.90
TSCA
No
RTECS
RN9781000

Empfohlen

Kürzlich angesehen

Chemikalien

Life science

Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf