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24280-93-1 - Mycophenolic acid, 98% - J61905 - Alfa Aesar

J61905 Mycophenolic acid, 98%

CAS-Nummer
24280-93-1
Synonyme

Größe Preis ($) Menge Verfügbarkeit
1g 34,70
5g 98,30
10g 171,00
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Mycophenolic acid, 98%

MDL
MFCD00036814
EINECS
246-119-3

Chemische Eigenschaften

Formel
C17H20O6
Molmasse
320.34
Form
Powder
Schmelzpunkt
139-141°
Löslichkeit
Soluble in methanol at 50mg/ml

Anwendungen

It is used as a small molecule IMPDH inhibitor. mycophenolic Acid is used as an immunosuppressive agent with antiviral and antitumor effects. It potently inhibits inosine monophosphate dehydrogenase, thus inhibiting de novo GTP synthesis leading to decreased RNA and DNA synthesis. It also reversibly inhibits proliferation of T and B lymphocytes and antibody formation.

Bemerkungen

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away from strong oxidizing agent.

Literaturverweise

Eugui et al. Lymphocyte-selective cytostatic and immunosuppressive effects of mycophenolic acid in vitro: role of deoxyguanosine nucleotide depeletion. Scand.J.Immunol. 1991, 33, (2), 161-73.

Allison et al. Mechanisms of action of mycophenolic acid. Ann.N.Y.Acad.Sci. 1993, 696, 63-87.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H302

Harmful if swallowed.

Sicherheitshinweise: P264-P270-P301+P312a-P330-P501a

Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Rinse mouth. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,6327
Beilstein
1295848
Harmonized Tariff Code
2941.90
TSCA
No
RTECS
MP8050000

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