Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

132-17-2 - Benzotropine methanesulfonate - Benztropine mesylate - Benztropine hydrobromidum - J61954 - Alfa Aesar

J61954 Benzotropine methanesulfonate

CAS-Nummer
132-17-2
Synonyme
Benztropine mesylate
Benztropine hydrobromidum

Größe Preis ($) Menge Verfügbarkeit
100mg 10,20
1g 20,40
5g 51,00
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

Benzotropine methanesulfonate

MDL
MFCD00074784
EINECS
205-048-8

Chemische Eigenschaften

Formel
C21H25NO.CH3SO3H
Molmasse
403.54
Form
Solid
Schmelzpunkt
135°
Löslichkeit
Soluble in water (81 mg/ml at 25°C), DMSO (50 mg/ml at 25°C), ethanol (81 mg/ml at 25°C), and ether (very slightly).

Anwendungen

Benzotropine methanesulfonate is used to treat the symptoms of Parkinson?s disease and is currently in clincial trials for chronic back pain. It shows anti-muscarinic effects comparable to Atropine, and also demonstrates competitive anti-nicotinic action at the nAChR (nicotinic acetylcholine receptor).

Bemerkungen

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agents. Store at 4°C.

Literaturverweise

Heidi Bisgaard; M Andreas B Larsen; Sonia Mazier; Thijs Beuming; Amy Hauck Newman; Harel Weinstein; Lei Shi; Claus J Loland; Ulrik Gether. The binding sites for benztropines and dopamine in the dopamine transporter overlap. Neuropharmacology. 2011, 60, (1), 182-190.

José A G Agúndez; Elena García-Martín; Hortensia Alonso-Navarro; Félix Javier Jiménez-Jiménez. Anti-Parkinson's disease drugs and pharmacogenetic considerations. Expert Opinion on Drug Metabolism and Toxicology. 2013, 9, (7), 859-874.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H301-H311-H331

Toxic if swallowed. Toxic in contact with skin. Toxic if inhaled.

Sicherheitshinweise: P261-P280h-P301+P310a-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/clothing. IF SWALLOWED: IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,1121
Gefahrenklasse
6.1
Verpackungsgruppe
III
Harmonized Tariff Code
2933.99
TSCA
No
RTECS
YM3150000

Empfohlen

  • A15457

    Diiodomethane, 99%, stab.
  • A18916

    Calcium formate, 98%
  • H31853

    Tris(2-dimethylaminoethyl)amine, 99+%
  • H52884

    4-n-Propylbenzeneboronic acid, 98%
  • H55315

    4-Nitrobenzenediazonium tetrafluoroborate, 97%

Kürzlich angesehen

Chemikalien

Life science

Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf