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50-14-6 - Calciferol, 98% - Ergocalciferol - Vitamin D<sub>2</sub> - J62163 - Alfa Aesar

J62163 Calciferol, 98%

CAS-Nummer
50-14-6
Synonyme
Ergocalciferol
Vitamin D2

Größe Preis ($) Menge Verfügbarkeit
1g 23,20
5g 91,70
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Calciferol, 98%

MDL
MFCD00166988
EINECS
200-014-9

Chemische Eigenschaften

Formel
C28H44O
Molmasse
396.66
Form
Powder
Schmelzpunkt
118-119°
Löslichkeit
Soluble in ethanol (80 mg/ml at 25°C), water (<1 mg/ml at 25°C), methanol, DMF (~20 mg/ml), and DMSO (20 mg/ml at 25°C).

Anwendungen

Vitamin D2 has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells. Vitamin D2 has also been shown to be an inhibitor of DNA polymerase. Vitamin D with calcium is used to treat or prevent bone loss (osteoporosis). Vitamin D is also used with other medications to treat low levels of calcium or phosphate caused by certain disorders (such as hypoparathyroidism, pseudohypoparathyroidism, familial hypophosphatemia). It may be used in kidney disease to keep calcium levels normal and allow normal bone growth.

Bemerkungen

Store at 4°C. Incompatible with heat and oxidizing agents.

Literaturverweise

Gui-Dong. Zhu.; William H. Okamura. Synthesis of Vitamin D (Calciferol).Chem. Rev. 1995, 95 (6),1877-1952 .

Maryka H. Bhattacharyya.; H.F. DeLuca. Subcellular location of rat liver calciferol-25-hydroxylase. Arch. Biochem. Biophys. 1974, 160 (1),58-62 .

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H301-H311-H330-H372

Toxic if swallowed. Toxic in contact with skin. Fatal if inhaled. Causes damage to organs through prolonged or repeated exposure.

Sicherheitshinweise: P260-P284-P280-P301+P310-P304+P340-P320-P330-P361-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear respiratory protection. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Specific treatment is urgent (see label). Rinse mouth. Remove/Take off immediately all contaminated clothing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,10018
Beilstein
1916682
Gefahrenklasse
6.1
Verpackungsgruppe
II
Harmonized Tariff Code
2936.29
TSCA
Yes
RTECS
KE1050000

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