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88150-42-9 - Amlodipine, 97+% - UK-48340 - J62242 - Alfa Aesar

J62242 Amlodipine, 97+%

CAS-Nummer
88150-42-9
Synonyme
UK-48340

Größe Preis ($) Menge Verfügbarkeit
1g 106,09
5g 407,88
10g 413,60
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Amlodipine, 97+%

MDL
MFCD00864687
EINECS
425-820-1

Chemische Eigenschaften

Formel
C20H25ClN2O5
Molmasse
408.88
Form
Crystalline powder
Schmelzpunkt
134-136°
Löslichkeit
Soluble in dimethyl sulfoxide, ethanol, water, dimethyl formamide, acetone, chloroform, ethyl acetate and methanol.

Anwendungen

A calcium channel antagonist with potent antioxidant activityAmlodipine is an L-type calcium channel protein inhibitor and blocker. It is used in combination with the angiotensin receptor blocker olmesartan. Further, it acts as a dihydropyridine calcium channel blocker. It is used as an anti-hypertensive. It is involved in the treatment of angina and to lower blood pressure. In addition to this, it is used to prevent chest pain and in coronary artery disease.

Bemerkungen

Incompatible with oxidizing agents.

Literaturverweise

Akamine, Y.; Uehara, H.; Miura, M.; Yasui-Furukori, N.; Uno, T. Multiple inductive effects of carbamazepine on combined therapy with paliperidone and amlodipine. J. Clin. Pharm. Ther. 2015, 40 (4), 480-482.

Norouzi, P.; Gupta, V. K.; Larijani, B.; Rasoolipour, S.; Faridbod, F.; Ganjali, M. R. Coulometric differential FFT admittance voltammetry determination of Amlodipine in pharmaceutical formulation by nano-composite electrode. Talanta 2015, 131, 577-584.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H301-H318-H373-H400-H410

Toxic if swallowed. Causes serious eye damage. May cause damage to organs through prolonged or repeated exposure. Very toxic to aquatic life. Very toxic to aquatic life with long lasting effects.

Sicherheitshinweise: P260-P273-P280-P264-P301+P310-P305+P351+P338-P310-P321-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Avoid release to the environment. Wear protective gloves/protective clothing/eye protection/face protection. Wash thoroughly after handling. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment (see label). Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,491
Gefahrenklasse
6.1
Verpackungsgruppe
III
Harmonized Tariff Code
2933.39
TSCA
No
RTECS
US7968329

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