J62311 Berberine chloride
SDS
| Größe | Preis ($) | Menge | Verfügbarkeit |
|---|---|---|---|
| 5g | 34,40 |
|
|
Berberine chloride
Chemische Eigenschaften
Anwendungen
Berberine is an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme Cox-2 (cyclooxygenase-2) which is abundantly expressed in colon cancer cells. Also inhibits c-Jun (Activator Protein 1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.
Bemerkungen
Literaturverweise
Shrinivas K. Kulkarni.; Ashish Dhir. Possible involvement of l-arginine-nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signaling pathway in the antidepressant activity of berberine chloride. Eur. J. Pharmacol. 2007, 569 (1-2),77-83 .
GHS Gefahren- und Sicherheitshinweise
Sicherheitshinweise: P260-P201-P280-P304+P340-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.
Weitere Referenzen
Chemikalien
Life science
Metalle und Stoffe
Katalysatoren
