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446-86-6 - Azathioprine - 6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine - J62314 - Alfa Aesar

J62314 Azathioprine

CAS-Nummer
446-86-6
Synonyme
6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine

Größe Preis ($) Menge Verfügbarkeit
1g 77,56
5g 228,80
10g 524,00
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Azathioprine

MDL
MFCD00069203
EINECS
207-175-4

Chemische Eigenschaften

Formel
C9H7N7O2S
Molmasse
277.26
Form
Crystalline powder
Löslichkeit
Soluble in Dichloromethane and dimethyl sulfoxide.

Anwendungen

Azathioprine is an immunosuppressive purine antimetabolite. The mechanism of action of azathioprine is as a nucleic acid synthesis inhibitor. It has shown promise in treatment of alopecia areata (autoimmune hair loss), with no difference in effectiveness between genders.

Bemerkungen

Store at -20°C. Incompatible with oxidizing agents. Protect from heat.

Literaturverweise

W.R. Connell.; Kamm.; Ritchie.; Prof J.E. Lennard-Jones.; Dickson.; A.M. Balkwill. Long-term neoplasia risk after azathioprine treatment in inflammatory bowel disease.The Lancet. 1994, 343 (8908),1249-1252 .

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H350-H302-H315-H319-H335

May cause cancer. Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P201-P261-P280-P281-P305+P351+P338-P304+P340-P362-P301+P312-P405-P501a

Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Use personal protective equipment as required. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,902
Harmonized Tariff Code
2933.59
TSCA
No
RTECS
UO8925000

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