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71-62-5 - Veratridine, 97+% - 3-Veratroylveracevine - J62324 - Alfa Aesar

J62324 Veratridine, 97+%

CAS-Nummer
71-62-5
Synonyme
3-Veratroylveracevine

Größe Preis ($) Menge Verfügbarkeit
50mg 521,00
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Veratridine, 97+%

MDL
MFCD00082515
EINECS
200-758-4

Chemische Eigenschaften

Formel
C36H51NO11
Molmasse
673.80
Form
Powder
Löslichkeit
Soluble in ethanol or DMSO. Freely soluble in chloroform. Also soluble in 1M HCl

Anwendungen

Veratridine causes Na+ channels to stay open during a sustained membrane depolarization by abolishing inactivation. This, in turn, opens voltage-activated calcium channels, thus increasing intracellular calcium content and inducing neurotransmitter release. Alkaloid neurotoxin which depolarizes excitable tissue; used to increase membrane sodium permeability.

Bemerkungen

Store at -20°C. Incompatible with oxidizing agents. Protect from heat.

Literaturverweise

Stephen R. Skilling.; David H. Smullin.; Alvin J. Beitz.; Alice A. Larson. Extracellular Amino Acid Concentrations in the Dorsal Spinal Cord of Freely Moving Rats Following Veratridine and Nociceptive Stimulation.J. Neurochem. 1988, 51 (1),127-132 .

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H300-H310-H330-H315-H319-H335

Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P301+P310a-P304+P340-P305+P351+P338-P320-P330-P405-P501a

IF SWALLOWED: Immediately call a POISON CENTER/doctor IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment is urgent (see label). Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,9954
Beilstein
78875
Gefahrenklasse
6.1
Verpackungsgruppe
I
Harmonized Tariff Code
2939.80
TSCA
No
RTECS
YX5600000

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