Brefeldin A mediated apoptosis has been observed in human tumor cellsIt is an antibiotic used in cell culture and to inhibit protein secretion in mammalian and other eukaryotic cells by interfering with the function of the Golgi apparatus.
Wase, N.; Tu, B.; Black, P. N.; DiRusso, C. C. Phenotypic screening identifies Brefeldin A/Ascotoxin as an inducer of lipid storage in the algae Chlamydomonas reinhardtii. Algal Res. 2015, 11, 74-84.
Fuchs, M.; Fîrstner, A. trans-Hydrogenation: Application to a Concise and Scalable Synthesis of Brefeldin A. Angew. Chem. 2015, 54 (13), 3978 -3982.
Gefahrenhinweise (EU): H302
Harmful if swallowed.
Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Rinse mouth. Dispose of contents/container in accordance with local/regional/national/international regulations.