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57444-62-9 - Resiniferatoxin, 99+% - J62458 - Alfa Aesar

J62458 Resiniferatoxin, 99+%

CAS-Nummer
57444-62-9
Synonyme

Größe Preis ($) Menge Verfügbarkeit
1mg 101,00
5mg 407,00
10mg 721,00
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Resiniferatoxin, 99+%

MDL
MFCD00135927

Chemische Eigenschaften

Formel
C37H40O9
Molmasse
628.71
Form
Solid
Löslichkeit
Soluble in DMSO to 100mM and to 50mM in ethanol

Anwendungen

Resiniferatoxin, a potent capsaicin-like stimulator of peripheral nociceptors in the neonatal rat tail in vitro. Resiniferatoxin is used as an anti-inflammatory, anti-viral and anti-psoriatic uses. Diterpene ester related to phorbol but apparently not tumorigenic activates protein kinase C

Bemerkungen

Resiniferatoxin (RTX) is susceptible to slow degradation if exposed to air. Even at -20°C, Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep in a dry place. Keep away from strong oxidizing agents. RTX must be stored in an inert atmosphere for long-term stability.

Literaturverweise

Szolcsanyi et al. Resiniferatoxin: an ultrapotent selective modulator of capsaicin-sensitive primary afferent neurons. J.Pharmacol.Exp.Ther. 1990, 255, (2), 923-8.

Winter et al. Cellular mechanism of action of resiniferatoxin: a potent sensory neuron excitotoxin. Brain Res. 1990, 520, (1-2), 131-40.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H301-H315-H319-H335

Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280a-P301+P310a-P305+P351+P338-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Beilstein
5371150
Gefahrenklasse
6.1
Verpackungsgruppe
III
Harmonized Tariff Code
3002.90
TSCA
No
RTECS
CY1633700

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