Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

136632-32-1 - Calpain Inhibitor II, 95+% - N-Ac-Leu-Leu-Methioninal - ALLM - J62491 - Alfa Aesar

J62491 Calpain Inhibitor II, 95+%

CAS-Nummer
136632-32-1
Synonyme
N-Ac-Leu-Leu-Methioninal
ALLM

Größe Preis ($) Menge Verfügbarkeit
5mg 64,80
25mg 269,86
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

Calpain Inhibitor II, 95+%

MDL
MFCD00065506

Chemische Eigenschaften

Formel
C19H35N3O4S
Molmasse
401.60
Form
Powder
Löslichkeit
Soluble in ethanol at 20mg/ml

Anwendungen

ALLM (Calpain Inhibitor) is a cell-permeable, peptide aldehyde inhibitor of calpain I and calpain II. ALLM acts as a very potent inhibitor of cathepsin L and the strongest inhibitor of cathepsin B amongst the peptide aldehydes. This compound inhibits the processing of malaria aspartic hemoglobinases plasmepsins I and II in vitro. ALLM also inhibits other neutral cysteine proteases, and activation-induced programmed cell death. It restores defective immune responses in HIV+ donors. ALLM blocks nitric oxide production by activated macrophages by interfering with transcription of the inducible nitric oxide synthase gene. ALLM also acts as a weak inhibitor of proteasome.

Bemerkungen

Store at -20°C. Incompatible with oxidizing agents. Protect from heat.

Literaturverweise

Sonia del Cerro.; John Larson.; Michael W. Oliver.; Gary Lynch. Development of hippocampal long-term potentiation is reduced by recently introduced calpain inhibitors.Brain Research. 1990, 530 (1),91-95 .

Weitere Referenzen

Beilstein
7693643
Harmonized Tariff Code
2930.90
TSCA
No

Empfohlen

  • 42747

    Methyl Green, 0.1% w/v aq. soln.
  • H63347

    2,4-Dichloro-3-cyanopyridine, 95%

Kürzlich angesehen

Chemikalien

Life science

Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf