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Camptothecin is used as a cytotoxic antitumor agent that inhibits topoisomerase I.Camptothecin shows remarkable anticancer activity based on preliminary clinical trials. Its analogues are used in cancer chemotherapy. Cyclodextrin-based polymer containing camptothecin is used in the investigational anti-cancer drug study.
Li, R.; Shu, C.; Wang, W.; Wang, X.; Li, H.; Xu, D.; Zhong, W. Encapsulation of 10-Hydroxy Camptothecin in Supramolecular Hydrogel as an Injectable Drug Delivery System. J. Pharm. Sci. 2015, 104 (7), 2266-2275.
Liu, Y. Q.; Li, W. Q.; Natschke, S. L. M.; Qian, K.; Yang, L.; Zhu, G. X.; Wu, X. B.; Chen, A. L.; Zhang, S. Y.; Nan, X.; Lee, K. H. Perspectives on Biologically Active Camptothecin Derivatives. Med Res Rev 2015, 35 (4), 753-789.
Gefahrenhinweise (EU): H301
Toxic if swallowed.
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.