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HEPES is common buffer for biological sciences, particularly used in cell culture to maintain physiological pH. It acts a buffering component, which is used in the preparation of buffers. It is described as one of the best all-purpose buffers available for use in biological research.
Johnson, S. E.; Hudson, J. L.; Kapur, J. Synchronization of action potentials during low-magnesium-induced bursting. J. Neurophysiol. 2015, 113 (7), 2461-2470.
Torelli, N. Q.; Ferreira-Júnior, J. R.; Kowaltowski, A. J.; da Cunha, F. M. RTG1-and RTG2-dependent retrograde signaling controls mitochondrial activity and stress resistance in Saccharomyces cerevisiae. Free Radical Biol. Med. 2015, 81, 30-37.