Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

21829-25-4 - Nifedipine, 98% - J62811 - Alfa Aesar

J62811 Nifedipine, 98%

CAS-Nummer
21829-25-4
Synonyme

Größe Preis ($) Menge Verfügbarkeit
5g 33,10
25g 193,00
100g 444,00
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

Nifedipine, 98%

MDL
MFCD00057326
EINECS
244-598-3

Chemische Eigenschaften

Formel
C17H18N2O6
Molmasse
346.33
Form
Powder
Schmelzpunkt
171-175°
Löslichkeit
Soluble in acetone, methylene chloride, chloroform, ethyl acetate, dimethyl sulfoxide and methanol. Sparingly soluble in ethanol. Insoluble in water.

Anwendungen

L-type calcium channel blocker; induces apoptosis in human glioblastoma cells.Nifedipine is a dihydropyridine calcium channel blocker used as L-type calcium channel blocker, antianginal and an antihypertensive . It induces apoptosis in human glioblastoma cells. It is used as a coronary vasodilator in the treatment of cardiac and circulatory disorders. Further, it is used in high-altitude medicine to treat high altitude pulmonary edema, hypertension and chronic stable angina. In addition, it is frequently used as a tocolytic agent.

Bemerkungen

Light sensitive. Store in a cool place. Incompatible with strong acids, strong oxidizing agents, caustics, aliphatic amines, amides, diethylamine, potassium hydride and potassium hydroxide.

Literaturverweise

Weerapol, Y.; Limmatvapirat, S.; Jansakul, C.; Takeuchi, H.; Sriamornsak, P. Enhanced dissolution and oral bioavailability of nifedipine by spontaneous emulsifying powders: Effect of solid carriers and dietary state. Eur. J. Pharm. Biopharm. 2015, 91, 25-34.

Miao, X. N.; Siu, K. L.; Cai, H. Nifedipine attenuation of abdominal aortic aneurysm in hypertensive and non-hypertensive mice: Mechanisms and implications. J. Mol. Cell. Cardiol. 2015, 87, 152-159.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H302

Harmful if swallowed.

Sicherheitshinweise: P264-P270-P301+P312a-P330-P501a

Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Rinse mouth. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,6528
Harmonized Tariff Code
2933.39
TSCA
No
RTECS
US7975000

Empfohlen

  • A10329

    Magnesium nitrate hexahydrate, 98%
  • A10446

    4-Chloro-3,5-dinitrobenzotrifluoride, 97%
  • A10884

    Diphenylsilane, 97%
  • A14715

    2-Iodoacetamide, 98%, stab. with ca 5-8% water
  • J62168

    Amiloride hydrochloride dihydrate

Kürzlich angesehen

Chemikalien

Life science

Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf