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51481-61-9 - Cimetidine, 98+% - 1-Cyano-3-methyl-2-[2-(5-methyl-4-imidazolylmethylthio)ethyl]guanidine - SKF-92334 - J62825 - Alfa Aesar

J62825 Cimetidine, 98+%

CAS-Nummer
51481-61-9
Synonyme
1-Cyano-3-methyl-2-[2-(5-methyl-4-imidazolylmethylthio)ethyl]guanidine
SKF-92334

Größe Preis ($) Menge Verfügbarkeit
5g 70,40
10g 95,90
25g 204,00
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

Cimetidine, 98+%

MDL
MFCD00133296
EINECS
257-232-2

Chemische Eigenschaften

Formel
C10H16N6S
Molmasse
252.34
Form
Powder
Schmelzpunkt
139-144°
Löslichkeit
Soluble to 50 mM in water and to 100 mM in DMSO, solubility in HCl (almost transparency).

Anwendungen

Widely used H2 histamine antagonist which has more recently been described as an inverse agonist. Also a potent I1 imidazoline binding site ligand. It displays antitumor and immunomodulatory activity. Cimetidine competitively inhibits histamine binding to histamine H2 receptors, and suppresses the growth of several tumors, including gastrointestinal cancer. This compound is an anti-angiogenic agent and is an activator of Nischarin. Competitive histamine H2-receptor antagonist which inhibits gastric acid secretion and reduces pepsin output

Bemerkungen

Store away from heat and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literaturverweise

Yasui-Furukori N, et al. Different effects of three transporting inhibitors, verapamil, cimetidine, and probenecid, on fexofenadine pharmacokinetics.Clinical pharmacology and therapeutics.,2005,77(1), 17-23.

Yoshizawa F, et al. Time course of leucine-induced 4E-BP1 and S6K1 phosphorylation in the liver and skeletal muscle of rats.Journal of clinical pharmacology.,1981,21(2), 87-91.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H303-H360

May be harmful if swallowed. May damage fertility or the unborn child.

Sicherheitshinweise: P201-P280-P312a-P308+P313-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. Call a POISON CENTER/doctor if you feel unwell. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,2279
Harmonized Tariff Code
2933.29
TSCA
No
RTECS
MF0035500

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