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7059-24-7 - Chromomycin A3, 97% - J62927 - Alfa Aesar

J62927 Chromomycin A3, 97%

CAS-Nummer
7059-24-7
Synonyme

Größe Preis ($) Menge Verfügbarkeit
10mg 307,00
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Chromomycin A3, 97%

MDL
MFCD00043151
EINECS
230-348-0

Chemische Eigenschaften

Formel
C57H82O26
Molmasse
1183.30
Form
Powder
Schmelzpunkt
185° dec.
Löslichkeit
Soluble in ethanol, DMSO, and ethyl acetate (10 mg/ml).

Anwendungen

Chromomycin A3, is used as a G-C specific DNA ligand which inhibits transcription and acts as a DNA binding dye. Chromomycin A3 antagonizes enhanced DNA binding of the transcription factors Sp1 and Sp3 to their cognate "G-C" box, induced by oxidative stress or DNA damage. Furthermore, by inhibiting transcription, Chromomycin A3 and its structural analogs can inhibit protein biosynthesis.

Bemerkungen

Research Use only: Not intended for animal or human diagnostic or therapeutic use.

Literaturverweise

CT Amemiya.;JR Gold. Chromomycin A3 stains nucleolus organizer regions of fish chromosomes. Copeia. 19861986 (1), 226-231.

RH Jensen. Chromomycin A3 as a fluorescent probe for flow cytometry of human gynecologic samples. Journal of Histochemistry & Cytochemistry. 197725 (7), 573-579.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H300-H360

Fatal if swallowed. May damage fertility or the unborn child.

Sicherheitshinweise: P201-P280-P301+P310a-P308+P313-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,2238
Gefahrenklasse
6.1
Verpackungsgruppe
I
Harmonized Tariff Code
2941.90
TSCA
No
RTECS
GB7875000

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