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138977-28-3 - Capsazepine, 99+% - J63055 - Alfa Aesar

J63055 Capsazepine, 99+%

CAS-Nummer
138977-28-3
Synonyme

Größe Preis ($) Menge Verfügbarkeit
10mg 144,00
50mg 596,00
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Capsazepine, 99+%

MDL
MFCD00153778

Chemische Eigenschaften

Formel
C19H21ClN2O2S
Molmasse
376.90
Form
Powder
Schmelzpunkt
159-161°
Löslichkeit
Soluble in ethanol or DMSO

Anwendungen

Capsazepine is shown to inhibit the development of mechanical hyperalgesia induced by intraplanar capsaicin injection. Capsazepine is described to block Resiniferatoxin (sc-24015)- and Capsaicin-induced contractions of guinea pig treacheal smooth muscle. Studies investigating the function of the VR1 (TRPV1 receptor) have employed Capsazepine as a tool for perturbing systemic neuronal response to Capsaicin.

Bemerkungen

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away from strong oxidizing agents.

Literaturverweise

Dickenson and Dray. Selective antagonism of capsaicin by capsazepine: evidence for a spinal receptor site in capsaicin-induced antinociception. Br.J.Pharmacol. 1991, 104, (4), 1045-9.

Kwak et al. A capsaicin-receptor antagonist, capsazepine, reduces inflammation-induced hyperalgesic responses in the rat: evidence for an endogenous capsaicin-like substance. Neuroscience. 1998, 86, (2), 619-26.

Weitere Referenzen

Harmonized Tariff Code
2933.99
TSCA
No

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Kürzlich angesehen

Chemikalien

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Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf