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951-77-9 - 2'-Deoxycytidine - J63062 - Alfa Aesar

J63062 2'-Deoxycytidine

CAS-Nummer
951-77-9
Synonyme

Größe Preis ($) Menge Verfügbarkeit
1g 23,20
5g 69,40
25g 277,00
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

2'-Deoxycytidine

MDL
MFCD00006547
EINECS
213-454-1

Chemische Eigenschaften

Formel
C9H13N3O4
Molmasse
227.22
Form
Crystalline powder
Schmelzpunkt
209-211°
Löslichkeit
Soluble in water, DMSO.

Anwendungen

2?-Deoxycytidine (deoxyC) is one of the deoxynucleosides which after phosphorylation to dCTP is used to synthesis DNA via various DNA polymerases or reverse transcriptases. 2?-Deoxycytidine (deoxyC) is the substrate for deoxycytidine deaminase (EC 3.5.4.14) which converts it into 2?-deoxyuridine. 2?-Deoxycytidine is phosphorylated to the nucleotide dCMP by the enzyme deoxycytidine kinase (DCK).

Bemerkungen

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents. Stable under recommended storage conditions.

Literaturverweise

JK Christman. 5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy. Oncogene. 200221 (35), 5483-5495.

LW Herte.; GB Boder.; JS Kroin.; SM Rinzel, GA Poore. Evaluation of the antitumor activity of gemcitabine (2?, 2?-difluoro-2?-deoxycytidine). Cancer research. 199050 (1), 4417-4419.

Weitere Referenzen

Beilstein
87567
Harmonized Tariff Code
2934.99
TSCA
Yes
RTECS
HA3800000

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