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10236-47-2 - Naringin - 4',5,7-Trihydroxyflavanone 7-rhamnoglucoside - J63166 - Alfa Aesar

J63166 Naringin

CAS-Nummer
10236-47-2
Synonyme
4',5,7-Trihydroxyflavanone 7-rhamnoglucoside

Größe Preis ($) Menge Verfügbarkeit
25g 27,81
100g 110,74
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Naringin

MDL
MFCD00148888
EINECS
233-566-4

Chemische Eigenschaften

Formel
C27H32O14
Molmasse
580.53
Form
Powder
Löslichkeit
Soluble in water, alcohol, acetone and warm acetic acid.

Anwendungen

A citrus bioflavanoid that inhibits cytochrome P-450 monooxygenase activityNaringin is used to prepare naringin dihydrochalcone, which is about 300-1800 times sweeter than sugar. It is a citrus bioflavonoid reported to inhibit cytochrome P450 monooxygenase activity. It also acts as an inhibitor of cytochrome P450 enzymes. It is employed as an antioxidant, lipid lowering and anticancer agent. In addition to this, it is used in a study to assess aldosterone production by a human adrenocortical cell line and to improve cognitive deficits of Alzheimer's disease.

Bemerkungen

Incompatible with strong oxidizing agents.

Literaturverweise

Nguyen, M. A.; Staubach, P.; Tamai, I.; Langguth, P. High-dose short-term administration of naringin did not alter talinolol pharmacokinetics in humans. Eur. J. Pharm. Sci. 2015, 68, 36-42.

Pai, D. A.; Vangala, V. R.; Ng, J. W.; Ng, W. K.; Tan, R. B. H. Resistant maltodextrin as a shell material for encapsulation of naringin: Production and physicochemical characterization. J. Food Eng. 2015, 161, 68-74.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,6425
Beilstein
102012
Harmonized Tariff Code
2938.90
TSCA
Yes
RTECS
QN6340000

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