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15686-71-2 - Cephalexin hydrate, 97+% - J63172 - Alfa Aesar

J63172 Cephalexin hydrate, 97+%

CAS-Nummer
15686-71-2
Synonyme

Größe Preis ($) Menge Verfügbarkeit
5g 57,90
25g 217,00
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Cephalexin hydrate, 97+%

MDL
MFCD00167148
EINECS
239-773-6

Chemische Eigenschaften

Formel
C16H17N3O4S•xH2O
Molmasse
347.39(anhy)
Form
Powder
Löslichkeit
Soluble in DMSO and Methanol.

Anwendungen

Cephalexin is a cephalosporin antibiotic used to study the effect of expression, binding, and inhibition of PBP3 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis. Cephalexin disrupts the synthesis of the peptidoglycan layer of bacterial cell walls which is responsible for cell wall structural integrity. Peptidoglycan synthesis is facilitated by transpeptidases known as penicillin-binding proteins (PBPs). PBPs bind to the D-Ala-D-Ala at the end of muropeptides (peptidoglycan precursors) to crosslink the peptidoglycan. Cephalexin antibiotics mimic the D-Ala-D-Ala site, thereby competitively inhibiting PBP crosslinking of peptidoglycan.

Bemerkungen

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.

Literaturverweise

Tomoko Sugiura et. al. PDZK1 regulates two intestinal solute carriers (Slc15a1 and Slc22a5) in mice. Drug Metabolism and Disposition. 200836 (6), 1181-1188.

Karolina Langowska et. al. Polymer nanoreactors shown to produce and release antibiotics locally. Chemical Communications. 201349 (2), 128-130 .

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H334-H317

May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction.

Sicherheitshinweise: P284-P261-P280g-P342+P311a-P363-P501a

Wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves. If experiencing respiratory symptoms: Call a POISON CENTER/doctor. Wash contaminated clothing before reuse. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,1974
Beilstein
965503
Harmonized Tariff Code
2941.90
TSCA
No
RTECS
XI0350000

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