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Ebselen inhibits 5-LO, CO, NADPH oxidize, and protein kinase C. It is a potent antioxidant. It possesses a unique glutathione peroxidase-like activity. It is also shown to be an inhibitor of free radical induced apoptosis and neuroprotective agent.
Helmut Sies. Ebselen, a selenoorganic compound as glutathione peroxidase mimic. Free Radical Biology and Medicine. 1993, 14,(3), 313-323.
Tankred Schewe. Molecular actions of Ebselenan anti-inflammatory antioxidant. General Pharmacology: The Vascular System. 1995, 26,(6), 1153-1169.
Gefahrenhinweise (EU): H331-H373
Toxic if inhaled. May cause damage to organs through prolonged or repeated exposure.
Do not breathe dust/fume/gas/mist/vapours/spray. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER/doctor. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.