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50-07-7 - Mitomycin C - J63193 - Alfa Aesar

J63193 Mitomycin C

CAS-Nummer
50-07-7
Synonyme

Größe Preis ($) Menge Verfügbarkeit
10mg 150,00
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Mitomycin C

MDL
MFCD00078109
EINECS
200-008-6

Chemische Eigenschaften

Formel
C15H18N4O5
Molmasse
334.33
Form
Powder
Schmelzpunkt
360°
Löslichkeit
Soluble in methanol, water and dimethyl sulfoxide.

Anwendungen

Mitomycin C is used as a chemotherapeutic agent due to its antitumor activity. It is used to treat upper gastro-intestinal cancers. It serves as an antineoplastic agent which inhibits DNA synthesis and induces apoptosis.

Bemerkungen

Store in a cool place. Incompatible with strong oxidizing agents, strong bases and strong acids.

Literaturverweise

Yan, C.; Kong, D.; Ge, D.; Zhang, Y.; Zhang, X.; Su, C.; Cao, X. Mitomycin C Induces Apoptosis in Rheumatoid Arthritis Fibroblast-Like Synoviocytes via a Mitochondrial-Mediated Pathway. Cell. Physiol. Biochem. 2015, 35 (3), 1125-1136.

Tai, T. Y. T.; Moster, M. R.; Pro, M. J.; Myers, J. S.; Katz, L. J. Needle Bleb Revision With Bevacizumab and Mitomycin C Compared With Mitomycin C Alone for Failing Filtration Blebs. J. Glaucoma 2015, 24 (4), 311-315.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H300-H351

Fatal if swallowed. Suspected of causing cancer.

Sicherheitshinweise: P201-P281-P264-P270-P301+P310-P308+P313-P321-P330-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF exposed or concerned: Get medical advice/attention. Specific treatment (see label). Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,6215
Beilstein
7231816
Gefahrenklasse
6.1
Verpackungsgruppe
II
Harmonized Tariff Code
2941.90
TSCA
Yes
RTECS
CN0700000

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