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4,5',8-Trimethylpsoralen is used for treatment of psoriasis, and as a photochemical crosslinker of DNA used as a probe for nucleic acid structure, used to crosslink DNA onto mica surfaces, mutagenesis of N2 worms.
Aba Losi.; Roberta Bedotti.; Cristiano Viappiani. Time-Resolved Photoacoustics Determination of Intersystem Crossing and Singlet Oxygen Photosensitization Quantum Yields for 4,5',8-Trimethylpsoralen.J. Phys. Chem.1995, 99, (43), 16162-16167.
Kandallu R. Kumaresan.; Muthukumar Ramaswamy.; Anthony T. Yeung. Structure of the DNA interstrand crosslink of 4,5',8-trimethylpsoralen.Biochemistry.1992, 31, (29), 6774-6783.
Gefahrenhinweise (EU): H314-H318
Causes severe skin burns and eye damage. Causes serious eye damage.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.