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64603-90-3 - Isoguvacine hydrochloride, 99% - 1,2,3,6-Tetrahydro-4-pyridinecarboxylic acid hydrochloride - J63243 - Alfa Aesar

J63243 Isoguvacine hydrochloride, 99%

CAS-Nummer
64603-90-3
Synonyme
1,2,3,6-Tetrahydro-4-pyridinecarboxylic acid hydrochloride

Größe Preis ($) Menge Verfügbarkeit
100mg 358,44
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Isoguvacine hydrochloride, 99%

MDL
MFCD00055192

Chemische Eigenschaften

Formel
C6H9NO2•HCl
Molmasse
163.60
Form
Powder
Löslichkeit
Soluble in water

Anwendungen

Isoguvacine·HCl is an agonist of γ-amino butyric acid receptor. Isoguvacine interactions have many similar biochemical features of GABA synaptic function. Isoguvacine·HCl is a specific GABAA receptor agonist. This compound suppresses low magnesium induced seizure like events in organotypic hippocampal brain slices.

Bemerkungen

Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Literaturverweise

Willian Seiji Korim.; Simon McMullan.; Sergio L. Cravo.; Paul M. Pilowsky. Asymmetrical changes in lumbar sympathetic nerve activity following stimulation of the sciatic nerve in rat. Brain Research. 2011, 1391, 60-70.

Takako Shimidzu.; Yoshinori Itoh.; Michiko Oka.; Tsuyoshi Ishima.; Yojiro Ukai.; Yoshiaki Yoshikuni.; Kiyoshi Kimura. Effect of a novel cognition enhancer NS-105 on learned helplessness in rats: Possible involvement of GABAB receptor up-regulation after repeated treatment. European Journal of Pharmacology. 1997, 338,(3), 225-232.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Harmonized Tariff Code
2933.39
TSCA
No
RTECS
US5908286

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