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27848-84-6 - Nicergoline - 5-Bromonicotinic acid 10-methoxy-1,6-dimethylergoline-8-methyl ester - J63295 - Alfa Aesar

J63295 Nicergoline

CAS-Nummer
27848-84-6
Synonyme
5-Bromonicotinic acid 10-methoxy-1,6-dimethylergoline-8-methyl ester

Größe Preis ($) Menge Verfügbarkeit
100mg 75,60
1g 237,93
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Nicergoline

MDL
MFCD00869626
EINECS
248-694-6

Chemische Eigenschaften

Formel
C24H26BrN3O3
Molmasse
484.39
Form
Powder
Löslichkeit
Soluble in alcohol, chloroform, and acetone. Insoluble in water.

Anwendungen

Nicergoline is an ergot derivative and vasodilator which increases blood flow in the brain. Nicergoline inhibits the vasoconstrictor effect of catecholamines by inhibiting the postsynaptic α1-adrenoceptors on vascular smooth muscle.

Bemerkungen

Protect from heat. Store away from oxidizing agents.

Literaturverweise

Arcamone, F.; Glasser, A.G.; Grafnetterov, J.; Minghetti, A.; Nicolella, V. TStudies on the metabolism of ergoline derivatives: Metabolism of nicergoline? in man and in animals.BBiochemical Pharmacology.1972, 21, (16), 2205-2213.

Bengt Winblad.; Mario Fioravanti.; Tomas Dolezal.; Inara Logina.; Ivan Gospodinov Milanov.; Dinu Cristian Popescu.; Alina Solomon. Therapeutic Use of Nicergoline.Clinical Drug Investigation.2008, 28, (9), 533-552.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H302

Harmful if swallowed.

Sicherheitshinweise: P264-P270-P301+P312-P330-P501a

Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,6496
Harmonized Tariff Code
2939.69
TSCA
No
RTECS
KE6341000

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