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1115-70-4 - 1,1-Dimethylbiguanide hydrochloride - Metformin hydrochloride - J63361 - Alfa Aesar

J63361 1,1-Dimethylbiguanide hydrochloride

CAS-Nummer
1115-70-4
Synonyme
Metformin hydrochloride

Größe Preis ($) Menge Verfügbarkeit
5g 26,57
25g 77,15
100g 231,75
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1,1-Dimethylbiguanide hydrochloride

MDL
MFCD00012582
EINECS
214-230-6

Chemische Eigenschaften

Formel
C4H11N5•HCl
Molmasse
165.62
Form
Powder
Schmelzpunkt
218-226°
Löslichkeit
Soluble in water (50 mg/ml), ethanol, and DMSO (50 mM).

Anwendungen

1,1-Dimethylbiguanide hydrochloride is used as an antidiabetic agent, used in polycystic ovary syndrome, non-alcoholic fatty liver disease and diabetes mellitus type 2. It may also reduce weight gain in people taking atypical antipsychotics, used in a study to investigate its role in enhancing the secretions of plasma active glucagon-like peptide-1 (GLP-1) levels.

Bemerkungen

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Literaturverweise

Cinquina, A.L.; Longo, F.; Calı?, A.; De Santis, L.; Baccelliere, R.; Cozzani, R.Validation and comparison of analytical methods for the determination of histamine in tuna fish samples. Journal of Chromatography A.2004, 1032, (1-2), 79-85.

Nobuyuki Yasuda.; Takashi Inoue.; Tadashi Nagakura.; Kazuto Yamazaki.; Kazunobu Kira.; Takao Saeki.; Isao Tanaka. Enhanced secretion of glucagon-like peptide 1 by biguanide compounds. Biochemical and Biophysical Research Communications.2002, 298, (5), 779-784.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H302-H315-H319

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation.

Sicherheitshinweise: P280-P264-P270-P305+P351+P338-P362-P301+P312-P321-P332+P313-P337+P313-P501a

Wear protective gloves/protective clothing/eye protection/face protection. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,5938
Harmonized Tariff Code
2925.29
TSCA
No
RTECS
DU1800000

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