Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

30562-34-6 - Geldanamycin, 99+% - NSC 122750 - U-29135 - J63397 - Alfa Aesar

J63397 Geldanamycin, 99+%

CAS-Nummer
30562-34-6
Synonyme
NSC 122750
U-29135

Größe Preis ($) Menge Verfügbarkeit
25mg 144,00
100mg 292,00
250mg 375,00
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

Geldanamycin, 99+%

MDL
MFCD00274570

Chemische Eigenschaften

Formel
C29H40N2O9
Molmasse
560.64
Form
Powder
Löslichkeit
Soluble in dimethyl sulfoxide at 100 mg/mL.

Anwendungen

Geldanamycin binds to and inhibits the cytosolic chaperone functions of heat shock protein 90 (HSP90). HSP90 maintains the stability and functional shape of many oncogenic signaling proteins. It interferes with conformational maturation of proteins and the cellular stress response. In addition, it is a potent inhibitor of the nuclear hormone receptor family.

Bemerkungen

Store in a cool dry place. Keep away from oxidizing agents. Protect from heat.

Literaturverweise

S. Mark Roe.; Chrisostomos Prodromou.; Ronan O'Brien.; John E. Ladbury.; Peter W. Piper.; Laurence H. Pearl. Structural Basis for Inhibition of the Hsp90 Molecular Chaperone by the Antitumor Antibiotics Radicicol and Geldanamycin.J. Med. Chem. 1999, 42 (2),260-266 .

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H303

May be harmful if swallowed.

Sicherheitshinweise: P312a

Call a POISON CENTER/doctor if you feel unwell.

Weitere Referenzen

Harmonized Tariff Code
2941.90
TSCA
No
RTECS
LX8920000

Empfohlen

Kürzlich angesehen

Chemikalien

Life science

Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf