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143-67-9 - Vinblastine sulfate, 98% - Vincaleukblastine sulfate - J63598 - Alfa Aesar

J63598 Vinblastine sulfate, 98%

CAS-Nummer
143-67-9
Synonyme
Vincaleukblastine sulfate

Größe Preis ($) Menge Verfügbarkeit
10mg 94,50
50mg 426,00
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Vinblastine sulfate, 98%

MDL
MFCD00082457
EINECS
205-606-0

Chemische Eigenschaften

Formel
C46H60N4O13S
Molmasse
909.06
Form
Powder
Schmelzpunkt
267°
Löslichkeit
Soluble in water and dimethylsulfoxide. Insoluble in ethanol.

Anwendungen

Anticancer agent; microtubule disrupter; Induces apoptosis.Vinblastine sulfate is therapeutically used as an antineoplastic. It is also used in the treatment of Hodgkin disease, choriocarcinoma, acute and chronic leukemias.

Bemerkungen

Store in a cool place. Hygroscopic. Incompatible with strong oxidizing agents and strong bases.

Literaturverweise

Lee, C. T.; Huang, Y. W.; Yang, C. H.; Huang, K. S. Drug Delivery Systems and Combination Therapy by Using Vinca Alkaloids. Curr. Top. Med. Chem. 2015, 15 (15), 1491-1500.

Chen, Q.; Bian, Y.; Zeng, S. Involvement of AP-1 and NF-κB in the Up-regulation of P-gp in Vinblastine Resistant Caco-2 Cells. Drug Metab. Pharmacokinet. 2014, 29 (2), 223-226.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H302-H315-H318-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye damage. May cause respiratory irritation.

Sicherheitshinweise: P260-P201-P280g-P304+P340-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,9982
Beilstein
3659812
Harmonized Tariff Code
2939.80
TSCA
No
RTECS
YY8400000

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