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66-76-2 - Dicumarol - Dicoumarol - 3,3'-Methylenebis(4-hydroxycoumarin) - J63634 - Alfa Aesar

J63634 Dicumarol

CAS-Nummer
66-76-2
Synonyme
Dicoumarol
3,3'-Methylenebis(4-hydroxycoumarin)

Größe Preis ($) Menge Verfügbarkeit
5g 30,10
25g 67,70
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Dicumarol

MDL
MFCD00006857
EINECS
200-632-9

Chemische Eigenschaften

Formel
C19H12O6
Molmasse
336.30
Form
Powder
Schmelzpunkt
286-289°
Löslichkeit
Soluble in aqueous alkaline solutions, organic bases, 0.1 N NaOH (15 mg/ml), Pyridine (50 mg/ml), chloroform (slightly soluble), and benzene (slightly soluble). Insoluble in water, and alcohols.

Anwendungen

Dicumarol is a natural chemical used as an anticoagulant agents that functions as a vitamin K antagonist and is also a derivative of Coumarin.

Bemerkungen

Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Literaturverweise

Joseph J Cullen; Marilyn M Hinkhouse; Matthew Grady; Andrew W Gaut; Jingru Liu; Yu Ping Zhang; Christine J Darby Weydert; Frederick E Domann; Larry W Oberley. Dicumarol inhibition of NADPH:quinone oxidoreductase induces growth inhibition of pancreatic cancer via a superoxide-mediated mechanism. Cancer Research. 2003, 63 (17),5513-5520.

Kathryn L. Armour et. al. Expression of human FcγRIIIa as a GPI-linked molecule on CHO cells to enable measurement of human IgG binding. Journal of Immunological Methods. 2010, 354 (1), 20-33.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H372-H302-H411

Causes damage to organs through prolonged or repeated exposure. Harmful if swallowed. Toxic to aquatic life with long lasting effects.

Sicherheitshinweise: P260-P273-P264-P270-P301+P312-P314-P330-P391-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Avoid release to the environment. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Get medical advice/attention if you feel unwell. Rinse mouth. Collect spillage. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,3090
Gefahrenklasse
6.1
Verpackungsgruppe
III
Harmonized Tariff Code
2932.20
TSCA
Yes
RTECS
GN7875000

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