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1177-87-3 - Dexamethasone acetate - J63691 - Alfa Aesar

J63691 Dexamethasone acetate

CAS-Nummer
1177-87-3
Synonyme

Größe Preis ($) Menge Verfügbarkeit
250mg 13,57
1g 42,15
5g 134,06
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Dexamethasone acetate

MDL
MFCD00027407
EINECS
214-646-8

Chemische Eigenschaften

Formel
C24H31FO6
Molmasse
434.50
Form
Powder
Schmelzpunkt
240°
Löslichkeit
Soluble at 100 mg/ml in acetone

Anwendungen

Dexamethasone has many uses in the treatment of cancer. Dexamethasone relieves inflammation in various parts of the body. To treat or prevent allergic reactions. As treatment of certain kinds of autoimmune diseases, skin conditions, asthma and other lung conditions. As treatment for a variety of cancers, such as leukemia, lymphoma, and multiple myeloma. It is also used for replacement therapy in adrenal insufficiency and in a screening test for the diagnosis of cushing's syndrome. Dexamethasone Acetate has also been determined to markedly decrease the number of activated macrophages. In addition, Dexamethasone Acetate has been observed to significantly decrease mRNA levels of TPH2 (tryptophan hydroxylase-2) in the raphe nuclei of C57/Bl6 mice.

Bemerkungen

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, heat.

Literaturverweise

Leibowitz HM,; Kupferman A,; Stewart RH,; Kimbrough RL.Evaluation of dexamethasone acetate as a topical ophthalmic formulation. . Am J Ophthalmol. . 1978, 86 (3), 418-23..

Roberts CP,; Murphy AA,; Santanam N,; Parthasarathy S. The effect of RU 486 and related compounds on cultured macrophage differentiation and function. Am J Obstet Gynecol.. 1996, 175 (2), 248-57.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H317

May cause an allergic skin reaction.

Sicherheitshinweise: P261-P280-P272-P363-P321-P333+P313-P302+P352-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Contaminated work clothing should not be allowed out of the workplace. Wash contaminated clothing before reuse. Specific treatment (see label). If skin irritation or rash occurs: Get medical advice/attention. IF ON SKIN: Wash with plenty of soap and water. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,2943
Beilstein
2342608
Harmonized Tariff Code
2937.22
TSCA
Yes
RTECS
TU4050000

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