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153559-49-0 - Bexarotene, 99+% - LGD-1069 - Targretin - J63701 - Alfa Aesar

J63701 Bexarotene, 99+%

CAS-Nummer
153559-49-0
Synonyme
LGD-1069
Targretin

Größe Preis ($) Menge Verfügbarkeit
100mg 135,00
300mg 316,00
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Bexarotene, 99+%

MDL
MFCD00932428

Chemische Eigenschaften

Formel
C24H28O2
Molmasse
348.48
Form
Powder
Schmelzpunkt
220-225°
Löslichkeit
Soluble in DMSO and ethanol

Anwendungen

Bexarotene is used as a Synthetic retinoid analog with specific affinity for the retinoid X receptor, an antineoplastic agent, already approved as an oral antineoplastic agent for cutaneous T cell lymphoma and being investigated against other cancers. A study has found that bexarotene in a mouse Alzheimer?s model lowered the most toxic form of β-amyloid peptide and increased cognitive ability.

Bemerkungen

Store in cool, dry conditions in well sealed containers. Keep container tightly closed.

Literaturverweise

Matthew N. Lowe.; Greg L. Plosker. Bexarotene. American Journal of Clinical Dermatology. 2000, 1, (4), 245-250.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,1194
Harmonized Tariff Code
2916.39
TSCA
No
RTECS
DH6834830

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