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Gossypol acts as an inhibitor for several dehydrogenase enzymes. Gossypol has also long been known to possess antimalarial properties. Gossypol provided reliable contraception. gossypol provokes infertility and causes spermatogenesis. Gossypol is used as an active antifertility agent in a variety of male animals, including mice, rats, hamsters, monkeys, rabbits, and bulls.
M.C. Chang,; Zhiping Gu (Chi-ping Ku),; S.K. Saksena. Effects of Gossypol on the fertility of male rats, hamsters and rabbits. Contraception. 1980, 21(5), 461-469.
Ying-Bo Mao,; Wen-Juan Cai,; Jia-Wei Wang,; Gao-Jie Hong. Silencing a cotton bollworm P450 monooxygenase gene by plant-mediated RNAi impairs larval tolerance of gossypo. Nature Biotechnology. 2007 , 251307 - 1313 .
Gefahrenhinweise (EU): H302-H341-H361
Harmful if swallowed. Suspected of causing genetic defects. Suspected of damaging fertility or the unborn child.
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