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2-Chloroadenosine is used as a selective A1-adenosine receptor agonist, and also Induces apoptosis.
Evans, M.C.; Swan, J.H.; Meldrum, B.S. An adenosine analogue, 2-chloroadenosine, protects against long term development of ischaemic cell loss in the rat hippocampus. Neuroscience Letters. 1987, 83, (3), 287-292.
Haslam, R.J.; Lynham, J.A. Activation and inhibition of blood platelet adenylate cyclase by adenosine or by 2-chloroadenosine. Life Sciences. 1972, 11, (23), 1143-1154.