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59588-86-2 - Alamethicin - U-22324 - J63829 - Alfa Aesar

J63829 Alamethicin

CAS-Nummer
59588-86-2
Synonyme
U-22324

Größe Preis ($) Menge Verfügbarkeit
1mg 97,00
5mg 394,00
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Alamethicin

MDL
MFCD00151517

Chemische Eigenschaften

Formel
C92H150N22O25
Molmasse
1964.40
Form
Powder
Schmelzpunkt
267-270°
Löslichkeit
Soluble in DMSO and ethanol.

Anwendungen

Alamethicin is used as a channel-forming ionophore that activates membrane enzymes, membrane channel-forming peptide. It is a 20-amino acid channel-forming peptide antibiotic that can function as a monovalent cation ionophore. Alamethicin has been used to develop methods for the routine assessment of potential new drug candidates to elicit their pharmacokinetic drug interactions.

Bemerkungen

Protect from heat. Store away from oxidizing agents.

Literaturverweise

Bechinger, B. Structure and Functions of Channel-Forming Peptides: Magainins, Cecropins, Melittin and Alamethicin. The Journal of Membrane Biology. 1997, 156, (3), 197 -211.

Gordon, L.G.M.; Haydon, D.A. The unit conductance channel of alamethicin. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1972, 255, (3), 1014-1018.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H301

Toxic if swallowed.

Sicherheitshinweise: P264-P270-P301+P310-P321-P330-P405-P501a

Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. Specific treatment (see label). Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Gefahrenklasse
6.1
Verpackungsgruppe
III
Harmonized Tariff Code
2933.99
TSCA
No
RTECS
AY1900000

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