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25316-40-9 - Doxorubicin hydrochloride - 14-Hydroxydaunomycin - J64000 - Alfa Aesar

J64000 Doxorubicin hydrochloride

CAS-Nummer
25316-40-9
Synonyme
14-Hydroxydaunomycin

Größe Preis ($) Menge Verfügbarkeit
10mg 167,00
50mg 352,00
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Doxorubicin hydrochloride

MDL
MFCD00077757
EINECS
246-818-3

Chemische Eigenschaften

Formel
C27H29NO11•HCl
Molmasse
579.99
Form
Solid
Schmelzpunkt
216° dec.
Löslichkeit
Soluble in water.

Anwendungen

Antitumor antibiotic agent that inhibits DNA topoisomerase II.Doxorubicin hydrochloride is used as an antineoplastic, antibiotic agent that inhibits DNA topoisomerase. It also inhibits nucleic acid synthesis and induces apoptosis. It posses fluorescent property, which enable it for the measurement of drug efflux pump activities and the role of subcellular organelles (golgi and lysosome) in the sequestration of drugs.

Bemerkungen

Moisture and light sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

Literaturverweise

Benival, D. M.; Devarajan, P. V. In Situ Lipidization as a New Approach for the Design of a Self Microemulsifying Drug Delivery System (SMEDDS) of Doxorubicin Hydrochloride for Oral Administration. J. Biomed. Nanotechnol. 2015, 11 (5), 913-922.

Esmaeili, A.; Hadad, N. A. Preparation of ZnFe2O4-chitosan-doxorubicin hydrochloride nanoparticles and investigation of their hyperthermic heat-generating characteristics. Ceram. Int. 2015, 41 (6), 7529-7535.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H302-H350

Harmful if swallowed. May cause cancer.

Sicherheitshinweise: P201-P280-P301+P312a-P308+P313-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,3439
Beilstein
4229251
Harmonized Tariff Code
2941.90
TSCA
No
RTECS
QI9295900

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