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2392-39-4 - Dexamethasone 21-phosphate disodium salt, 98% - J64083 - Alfa Aesar

J64083 Dexamethasone 21-phosphate disodium salt, 98%

CAS-Nummer
2392-39-4
Synonyme

Größe Preis ($) Menge Verfügbarkeit
1g 103,00
5g 321,00
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Dexamethasone 21-phosphate disodium salt, 98%

MDL
MFCD00079105
EINECS
219-243-0

Chemische Eigenschaften

Formel
C22H28FNa2O8P
Molmasse
516.40
Form
Powder
Schmelzpunkt
233-240°
Löslichkeit
Soluble in water. Slightly soluble in ethanol. Insoluble in dichloromethane.

Anwendungen

Dexamethasone 21-phosphate disodium salt acts as an inducer of apoptosis and inhibitor of the sodium phosphate symporter. It is used in the treatment of emetic effects of cancer therapy and epicondylitis. Further, it serves as an activator of food, medicine, glucocorticoid and anti inflammatory.

Bemerkungen

Hygroscopic. Incompatible with oxidizing agents.

Literaturverweise

Keeler, G. D.; Durdik, J. M.; Stenken, J. A. Effects of delayed delivery of dexamethasone-21-phosphate via subcutaneous microdialysis implants on macrophage activation in rats. Acta Biomater. 2015, 23, 27-37.

Ogawa, N.; Kanki, K.; Honda, K.; Tomooka, Y.; Ryoke, K.; Watanabe, T. Involvement of glucocorticoid in induction of lingual T1R3 in rodents. Eur. J. Pharmacol. 2015, 761, 262-267.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H351-H361-H302

Suspected of causing cancer. Suspected of damaging fertility or the unborn child. Harmful if swallowed.

Sicherheitshinweise: P201-P281-P264-P270-P202-P301+P312-P308+P313-P330-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. Do not handle until all safety precautions have been read and understood. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF exposed or concerned: Get medical advice/attention. Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,2943
Beilstein
6473066
Harmonized Tariff Code
2937.22
TSCA
Yes
RTECS
TU4056000

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Chemikalien

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Metalle und Stoffe

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