J64538 Cerulenin, 98%
SDS
| Stock No. | Größe | Preis ($) | Menge | Verfügbarkeit |
|---|---|---|---|---|
| J64538-#0 | 5mg | 113,00 |
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| J64538-MA | 10mg | 225,00 |
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Cerulenin, 98%
Chemische Eigenschaften
Anwendungen
Cerulenin is used as an antifungal antibiotic that inhibits sterol and fatty acids biosynthesis. Cerulenin induces apoptosis in tumor cell lines. It can be a useful biochemical tool with applications for the study of metabolism and function of fatty acids in the bacterial cell membrane and in yeast. An extensive review including the properties, uses, mechanism of action and structure has been reported.
Bemerkungen
Literaturverweise
Sakari Kauppinen.; Mads Siggaard-Andersen.; Penny von Wettstein-Knowles. β-ketoacyl-ACP synthase I of Escherichia coli: Nucleotide sequence of thefabB gene and identification of the cerulenin binding residue. Carlsberg Research Communications. 1988, 53, (6), 357-370.
Giuliano D'agnony.; Ira S. Rosenfeld.; Juichi Awaya.; Satoshi Omura.; Roy Vagelos, P. Inhibition of fatty acid synthesis by the antibiotic cerulenin: Specific inactivation of β-ketoacyl-acyl carrier protein synthesize. Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1973, 326, (2), 155-166.
GHS Gefahren- und Sicherheitshinweise
Gefahrenhinweise (EU): H302
Harmful if swallowed.
Sicherheitshinweise: P264-P270-P301+P312a-P330-P501a
Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. Dispose of contents/container in accordance with local/regional/national/international regulations.
Weitere Referenzen
Chemikalien
Life science
Metalle und Stoffe
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