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2'-Bromo-2'-deoxyuridine is a thymidine analogue which is incorporated into DNA. 5-BrdU is routinely and extensively used to measure DNA synthesis and to label dividing cells. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.
M.M. Ponpipom.; S. Hanessian. Novel access to 2?-deoxyuridine, and reactive intermediates to pyrimidine nucleosides. Carbohydrate Research. 1971, 17 (1), 741-750.
Etsuko Kawashima.; Yukio Aoyama.; Takeshi Sekine.; Eiichi Nakamura.; Masatsune Kainosho.; Yoshimasa Kyogoku.; Yoshiharu Ishido. Sonochemical and triethylborane-induced tin deuteride reduction for the highly stereoselective synthesis of (2?R)-[2?-2H]-2?-deoxyribonucleosides from 2?-functionalized ribonucleosides. Tetrahedron Letters. 1993, 34 (8), 1317-1320.