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364590-63-6 - Smoothened Agonist dihydrochloride dihydrate - SAG1.3 HCl - J64726 - Alfa Aesar

J64726 Smoothened Agonist dihydrochloride dihydrate

CAS-Nummer
364590-63-6
Synonyme
SAG1.3 HCl

Größe Preis ($) Menge Verfügbarkeit
1mg 120,00
5mg 428,00
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Smoothened Agonist dihydrochloride dihydrate

MDL
MFCD14636155

Chemische Eigenschaften

Formel
C28H28ClN3OS•2HCl.2H2O
Molmasse
599.00
Form
Solid
Sensitivität
Light Sensitive & Hygroscopic
Löslichkeit
Soluble in water.

Anwendungen

Smoothened Agonist, HCl (SAG), is a highly potent activator of Smo (smoothened). This chlorobenzothiophene compound is a hedgehog pathway agonist that interacts with the heptahelical domain of Smo. SAG is shown to act as an activator at low concentrations, but can inhibit Smo coupling at very high concentrations. The activating effects of SAG will counteract Cyclopamine or Cyclopamine-KAAD inhibition of Smo.

Bemerkungen

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers. It is sensitive to light. It is hygroscopic in nature. Protect from humidity and water. Store under dry inert gas.

Weitere Referenzen

Harmonized Tariff Code
2934.99
TSCA
No

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