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184901-82-4 - Tripeptidyl peptidase Inhibitor - H-AAF-CMK - TPPII Inhibitor - J64760 - Alfa Aesar

J64760 Tripeptidyl peptidase Inhibitor

CAS-Nummer
184901-82-4
Synonyme
H-AAF-CMK
TPPII Inhibitor

Größe Preis ($) Menge Verfügbarkeit
5mg 73,71
10mg 175,00
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

Tripeptidyl peptidase Inhibitor

MDL
MFCD01310850

Chemische Eigenschaften

Formel
C16H22ClN3O3
Molmasse
453.90
Form
Solid
Sensitivität
Light Sensitive
Löslichkeit
Soluble in water.

Anwendungen

Tripeptidyl peptidase Inhibitor is a serine protease inhibitor which irreversibly inhibits TPPII (tripeptidyl peptidase II), a giant protease which may substitute for some proteasome functions, and reversibly inhibits Cln (TPPI). AAF-CMK shows only marginal inhibition of the chymotrypsin-like activity of the proteasome.

Bemerkungen

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers. It is sensitive to light.

Literaturverweise

Ulrike Kuckelkorn.; Thomas Ruppert.; Britta Strehl.; Peter R. Jungblut.; Ursula Zimny-Arndt.; Stephanie Lamer.; Immo Prinz.; Ilse Drung.; Peter-M. Kloetzel.; Stefan H.E. Kaufmann.; Ulrich Steinhoff . Link between Organ-specific Antigen Processing by 20S Proteasomes and CD8+ T Cell-mediated Autoimmunity. JEM Home. 2002, 195, (8), 983.

Maria Luisa Gándara.; Pilar Lopez.; Raquel Hernando.; Jose G. Castano.; Susana Alemany. The COOH-Terminal Domain of Wild-Type Cot Regulates Its Stability and Kinase Specific Activity . The lancet. 1972, 299, (7750), 555-557.

Weitere Referenzen

Harmonized Tariff Code
3504.00
TSCA
No

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