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53-85-0 - 5,6-Dichlorobenzimidazole riboside, 98% - DBR - 5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole - J64870 - Alfa Aesar

J64870 5,6-Dichlorobenzimidazole riboside, 98%

CAS-Nummer
53-85-0
Synonyme
DBR
5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole

Größe Preis ($) Menge Verfügbarkeit
50mg 141,00
100mg 273,00
250mg 562,00
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

5,6-Dichlorobenzimidazole riboside, 98%

MDL
MFCD00036785

Chemische Eigenschaften

Formel
C12H12Cl2N2O4
Molmasse
319.14
Form
Powder
Löslichkeit
Soluble in DMSO to 75mMSoluble in dimethyl sulfoxide, hot ethanol, dimethyl formamide, (1:2) dimethyl formamide:Phosphate buffer saline, water, methanol and pyridine. Slightly soluble in aqueous buffers.

Anwendungen

Inhibits casein kinase II and blocks RNA synthesis. An adenosine analog.5,6-Dichlorobenzimidazole riboside is used as an inhibitor of RNA Polymerase II. It is nucleoside analogue and used in research to study the mechanisms of cellular regulation. Further, it inhibits some protein kinases.

Bemerkungen

Incompatible with heat and oxidizing agents.

Literaturverweise

Liu, Y.; He, X.; Sui, Y.; Yu, R.; Xu, G. Transcription factor IKZF1 is degraded during the apoptosis of multiple myeloma cells induced by kinase inhibition. FEBS Lett. 2015, 589 (17), 2233-2240.

Bartkowiak, B.; Greenleaf, A. L. Expression, Purification, and Identification of Associated Proteins of the Full-length hCDK12/CyclinK Complex. J. Biol. Chem. 2015, 290 (3), 1786-1795.

Weitere Referenzen

Beilstein
39123
Harmonized Tariff Code
2938.90
TSCA
No
RTECS
DD7310000

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Kürzlich angesehen

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Metalle und Stoffe

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