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4311-88-0 - Necrostatin-1 - Nec-1 - Necroptotic Inhibitor - J65341 - Alfa Aesar

J65341 Necrostatin-1

CAS-Nummer
4311-88-0
Synonyme
Nec-1
Necroptotic Inhibitor

Größe Preis ($) Menge Verfügbarkeit
20mg 103,00
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Necrostatin-1

MDL
MFCD00056916

Chemische Eigenschaften

Formel
C13H13N3OS
Molmasse
259.33
Form
Powder
Sensitivität
Light Sensitive
Löslichkeit
Soluble in DMSO (10-25 mg/ml), 100% ethanol (6 mg/ml), and methanol (5 mg/ml).

Anwendungen

Necrostatin-1 functions as an allosteric inhibitor of the death domain receptor-associated adaptor kinase RIP (RIP1) in the necroptosis pathway. While affecting this distinct cell death pathway, Necrostatin-1 does not present any perturbation of the Fas/TNFR triggered canonical apoptosis cascade.

Bemerkungen

Light sensitive. Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents, heat, light. Store in refrigerator.

Literaturverweise

T Suzuki; T Tomioka; K Tuzimura. Proton nuclear magnetic resonance studies on methylthiohydantoins, thiohydantoins, and hydantoins of amino acids. Canadian journal of biochemistry. 1977, 55, (5), 521-527.

Mabel Lum; Renato Morona. Dynamin-related protein Drp1 and mitochondria are important forShigella flexneriinfection. International Journal of Medical Microbiology. 2014, 304, (5-6), 530-541.

Weitere Referenzen

Harmonized Tariff Code
2933.99
TSCA
No

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Kürzlich angesehen

Chemikalien

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Metalle und Stoffe

Katalysatoren

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