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134448-10-5 - Cathepsin B Inhibitor III - CA-074 - [L-3-trans-(Propylcarbamoyl)oxirane-2-carbonyl]-L-isoleucyl-L-proline - J65347 - Alfa Aesar

J65347 Cathepsin B Inhibitor III

CAS-Nummer
134448-10-5
Synonyme
CA-074
[L-3-trans-(Propylcarbamoyl)oxirane-2-carbonyl]-L-isoleucyl-L-proline

Größe Preis ($) Menge Verfügbarkeit
5mg 289,00
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Cathepsin B Inhibitor III

MDL
MFCD00797531

Chemische Eigenschaften

Formel
C18H29N3O6
Molmasse
383.44
Form
Powder
Löslichkeit
Soluble in methanol at 1mg/ml. Also soluble in DMSO or ethanol.

Anwendungen

CA-074 is a potent and specific inhibitor of cathepsin B in vitro.

Bemerkungen

Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents, bases, heat. Store in refrigerator.

Literaturverweise

Lasse Foghsgaard; Dorte Wissing; Daniel Mauch; Ulrik Lademann; Lone Bastholm; Marianne Boes; Folmer Elling; Marcel Leist and Marja Jaattela. Cathepsin B Acts as a Dominant Execution Protease in Tumor Cell Apoptosis Induced by Tumor Necrosis Factor. JCB. 2001, 153, (5), 999-1010 .

Sajani S Lakka; Christopher S Gondi; Niranjan Yanamandra; William C Olivero; Dzung H Dinh; Meena Gujrati and Jasti S Rao. Inhibition of cathepsin B and MMP-9 gene expression in glioblastoma cell line via RNA interference reduces tumor cell invasion, tumor growth and angiogenesis. Oncogene. 2004, 23, 4681-4689.

GHS Gefahren- und Sicherheitshinweise

Sicherheitshinweise: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Harmonized Tariff Code
2934.99
TSCA
No

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