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Lipoprotein, low density, oxidized, human plasma, 99%, BT-910 - Ox-LDL - Oxidized LDL - J65591 - Alfa Aesar

J65591 Lipoprotein, low density, oxidized, human plasma, 99%, BT-910

CAS-Nummer
Synonyme
Ox-LDL
Oxidized LDL

Größe Preis ($) Menge Verfügbarkeit
2mg 223,00
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Lipoprotein, low density, oxidized, human plasma, 99%, BT-910

Chemische Eigenschaften

Form
Liquid

Anwendungen

Lipoprotein, low density, oxidized, human plasma, is evaluated for receptor binding to peritoneal macrophages. Furthermore, it is used to induce foam cell formation in macrophages.

Research on foam cell formation is relevant to the study of atherosclerosis. Cellular exposure to ox-LDL results in the formation of lipid droplets containing cholesteryl esters in the cytoplasm of the macrophage as the lipoprotein particles are metabolized by the cell.

Bemerkungen

Supplied at 2mg/ml in 1X phosphate-buffered saline at pH 7.4 and 0.3 mM EDTA. Contains gentamicin sulfate. Aseptically packaged and sterile filtered. Store at 4°C. Do not freeze. Short shelf life: up to 6 weeks. TBARS: 29-44 nmoles MDA/mg

Literaturverweise

Amezaga, N.; Sanjurjo, L.; Julve, J.; Aran, G.; Perez-Cebezas, B.; Bastos-Amador, P.; Armengol, C.; Vilella, R.; Escola-Gil, J. C.; Blanco-Vaca, F.; Borras, F. E.; Valledor, A. F.; Sarrias, M. -R. Human scavenger protein AIM increases foam cell formation and CD36-mediated oxLDL uptake. J Leukoc Bio 2013, 95 (3), 509-520.

Zhang, Y.; Ye, Y.; Wang, Y.; Chen, W. Inhibition of Lectin-Like Oxidized Low-Density Lipoprotein Receptor 1 Protects against Plasma/Hypoxia-Mediated Trophoblast Dysfunction Associated with Preeclampsia. Gynecol. Obstet. Invest. 2013, 79 (2), 90-96.

Zhang, Y.; Xie, Y.; You, S.; Han, Q.; Cao, Y.; Zhang, X.; Xiao, G.; Chen, R.; Liu, C. Autophagy and Apoptosis in the Response of Human Vascular Endothelial Cells to Oxidized Low-Density Lipoprotein. Cardiology 2015, 132 (1), 27-33.

Weitere Referenzen

Harmonized Tariff Code
2937.19
TSCA
No

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Kürzlich angesehen

Chemikalien

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Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf